effect of active pharmaceutical ingredients and plasticizers

effect of active pharmaceutical ingredients

Effect of Active Pharmaceutical Ingredients

Investigate the effect of active pharmaceutical ingredients (APIs) and plasticizers on the thermal clouding and gelation of solutions of hypromellose excipient polymers. Increasing knowledge in this area can aid in the development of liquid formulations and in under-standing the dissolution properties of solid dosage forms.

Get Price
influence of active pharmaceutical ingredients

Influence of active pharmaceutical ingredients

Influence of active pharmaceutical ingredients and plasticizers on processability of HPMC with FFF technology (Piotr Gruber, Małgorzata Rusińska, Grzegorz J. Ziółkowski, Konrad Szustakiewicz, Magdalena Tomanik, Patrycja E. Szymczyk), In 2019 Additive ...

Get Price
pharmaceutical plasticizers for drug delivery systems

Pharmaceutical Plasticizers for Drug Delivery Systems

The effect of plasticizers on the GC films casted using solvent evaporation method were evaluated in terms of uniformity of thickness, moisture absorption, water vapour transmission, tensile ...

Get Price
the effect of active pharmaceutical ingredients on aerosol

The Effect of Active Pharmaceutical Ingredients on Aerosol

The influence of different active pharmaceutical ingredients, formulated as solution pMDIs, on the aerosol performance and electrostatic charge profiles have been investigated in this study and results are discussed below. 3.1 The effect of APIs on overall aerosol net charge using different actuator materials

Get Price
pharmaceutical applications of plasticized polymers

Pharmaceutical Applications of Plasticized Polymers

Recent Advances in Plasticizers 70 pharmaceutical compositions of two kinds of coated beads were patented. The polymer coatings of the beads differed in water solubility. This pharmaceutical composition comprised phtalates, trimellitates, adipates, sebacates, glycols, polyethers and alkyl c itrates as the plasticizers (Paborji & Flugel 2011).

Get Price
the polymorphism effect in active pharmaceutical

The Polymorphism Effect in Active Pharmaceutical

The Polymorphism Effect in Active Pharmaceutical Ingredients (API): A Issue Affecting on Bioavailability And Bioequivalence of Drugs Letter to Editor The chemical and physical properties of the active pharmaceutical ingredients (API) on solid-state form can be affected by polymorphism effect. This effect can have a significant influence

Get Price
interactions between active pharmaceutical ingredients

Interactions between active pharmaceutical ingredients

Interactions between active pharmaceutical ingredients and excipients affecting bioavailability: impact on bioequivalence Eur J Pharm Sci. 2014 Dec 18;65:89-97. doi: 10.1016/j.ejps.2014.09.004. Epub 2014 Sep 16. Author Alfredo García-Arieta 1 Affiliation ...

Get Price
recrystallization of active pharmaceutical ingredients

Recrystallization of Active Pharmaceutical Ingredients

Recrystallization of Active Pharmaceutical Ingredients 187 The main effect of temperature on crystallizatio n from solution is secondary to its influence on the solubility of the solute, and subsequently the degr ee of saturation of the solution. Although molecular recognition is required for the formation of molecular clusters, and this

Get Price
effects of plasticizers and surfactants on the film

Effects of plasticizers and surfactants on the film

From the results it can be stated that plasticizers like PEG-400 at 1.5% and PG at 1% have a significant effect on the film forming property of HPMC. The films formed with HPMC + PEG400 (1.5%) were free from major defects like cracking, orange peel, and picking with good gloss and very slight chipping and splitting occasionally ( Mortada, 1990 ...

Get Price
plasticizer

Plasticizer

A plasticizer (UK: plasticiser) is a substance that is added to a material to make it softer and more flexible, to increase its plasticity, to decrease its viscosity, or to decrease friction during its handling in manufacture.. Plasticizers are commonly added to polymers such as plastics and rubber, either to facilitate the handling of the raw material during fabrication, or to meet the ...

Get Price
pharmaceutical applications of plasticized polymers

Pharmaceutical Applications of Plasticized Polymers

Recent Advances in Plasticizers 70 pharmaceutical compositions of two kinds of coated beads were patented. The polymer coatings of the beads differed in water solubility. This pharmaceutical composition comprised phtalates, trimellitates, adipates, sebacates, glycols, polyethers and alkyl c itrates as the plasticizers (Paborji & Flugel 2011).

Get Price
role of plasticizers in bioplastics

Role of plasticizers in bioplastics

use as commercial packaging materials. In this regard plasticizers provide the necessary workability to biopolymers. This review gives a brief insight into their plasticization effects, types, properties along with their effect and recent applications on bio-based materials, with special reference to a new class of plasticizers, Ionic liquids.

Get Price
quantitative analysis of active pharmaceutical ingredients

Quantitative analysis of active pharmaceutical ingredients

1 Quantitative analysis of active pharmaceutical ingredients (APIs) 2 using a potentiometric electronic tongue in a SIA flow system 3 4 M. Wesoły 1, X. Cetó 2, M. del Valle 2, P. Ciosek 1, W. Wróblewski *1 5 6 1Department of Microbioanalytics, Faculty of Chemistry, Warsaw University of 7 Technology, Noakowskiego 3, 00-664 Warsaw, Poland 8 2Sensors and Biosensors Group, Department of ...

Get Price
plasticizer compatibility and thermal and rheological

Plasticizer Compatibility and Thermal and Rheological

active pharmaceutical ingredient (API) recrystallization. The preferred polymer must also be amenable to the process technology. In hot-melt extrusion, thermal properties and melt rheology must be considered when selecting a formula. The glass transition temperature, T g, of the polymers defines the lower end of the

Get Price
calyx chemicals & pharmaceuticals limited | usdmf | active

Calyx Chemicals & Pharmaceuticals Limited | USDMF | Active

History Calyx Chemicals and Pharmaceuticals was originally incorporated as "Shree Deep Jyote Industrial Paints Private Limited" on January 14, 1986 under the Company Act, 1956 with the Registrar of Companies, Mumbai and was converted into a pubic limited company with effect from September 08, 2006.

Get Price
phthalate and organophosphate plasticizers in nail polish

Phthalate and Organophosphate Plasticizers in Nail Polish

The effect of the active phthalates on FSH-stimulated cAMP accumulation and lactate secretion is not dependent on the age of the animal over a range of 13-80 days, suggesting that the age-related toxicity in vivo may be related to differences in metab. and disposition rather than tissue sensitivity.

Get Price
international journal of international journal of medicine

International Journal of International Journal of Medicine

formulated using polymers, active pharmaceutical ingredients (API), plasticizers, saliva stimulating agents, sweeteners, flavors, preservatives and colors. Fast dissolving film is simply placed on the patient’s tongue or any oral mucosal tissue, instantly wet by saliva the film rapidly hydrates and adheres onto the site of application.

Get Price
taste masking of griseofulvin and caffeine anhydrous using

Taste Masking of Griseofulvin and Caffeine Anhydrous Using

Taste masking of bitter active pharmaceutical ingredient (API) is a major challenge especially for pediatric/geriatric formulations. Effective taste masking can be achieved by various reported approaches like fluidized-bed coating, supercritical fluids, complexing agents, pro-drug approach, etc. ( 1 – 3 ).

Get Price
a systemic approach on understanding the role of moisture

A systemic approach on understanding the role of moisture

Arigo A, Jawahar N, Nikhitha S, Arun R. Effect of hygroscopicity on pharmaceutical ingredients, methods to determine and overcome: an overview. J Chem Pharm Res 2018; 10: 61-67. Claes A, George Z. The molecular basis of moisture effects on the physical and chemical stability of drugs in the solid state. Int J Pharm 1990; 67: 87-95.

Get Price
pharmacompass – grow your pharma business digitally

PharmaCompass – Grow Your Pharma Business Digitally

PharmaCompass delivers the pharmaceutical information you need to make your decisions. Get FREE access to USDMFs, Prices, Inspections, Patents, FDA Orange Book, CEPs, News, GDUFA Status, Written Confirmations and much more.

Get Price
pharmaceutical applications of plasticized polymers

Pharmaceutical Applications of Plasticized Polymers

Recent Advances in Plasticizers 70 pharmaceutical compositions of two kinds of coated beads were patented. The polymer coatings of the beads differed in water solubility. This pharmaceutical composition comprised phtalates, trimellitates, adipates, sebacates, glycols, polyethers and alkyl c itrates as the plasticizers (Paborji & Flugel 2011).

Get Price
pharmaceutical excipients and drug metabolism: a mini

Pharmaceutical Excipients and Drug Metabolism: A Mini

Pharmaceutical excipients are ingredients other than the active pharmaceutical ingredient (API) present in a finished pharmaceutical drug formulation. These are frequently used as lubricants, diluent, binders, flavorings, coating and coloring agents for the formulation.

Get Price
quantitative analysis of active pharmaceutical ingredients

Quantitative analysis of active pharmaceutical ingredients

1 Quantitative analysis of active pharmaceutical ingredients (APIs) 2 using a potentiometric electronic tongue in a SIA flow system 3 4 M. Wesoły 1, X. Cetó 2, M. del Valle 2, P. Ciosek 1, W. Wróblewski *1 5 6 1Department of Microbioanalytics, Faculty of Chemistry, Warsaw University of 7 Technology, Noakowskiego 3, 00-664 Warsaw, Poland 8 2Sensors and Biosensors Group, Department of ...

Get Price
international journal of international journal of medicine

International Journal of International Journal of Medicine

formulated using polymers, active pharmaceutical ingredients (API), plasticizers, saliva stimulating agents, sweeteners, flavors, preservatives and colors. Fast dissolving film is simply placed on the patient’s tongue or any oral mucosal tissue, instantly wet by saliva the film rapidly hydrates and adheres onto the site of application.

Get Price
hot-melt extrusion with - basf

Hot-Melt Extrusion with - BASF

10.2.2 Infl uence of Plasticizers on Melt Viscosity 116 10.3 Decomposition by TGA 116 10.3.1 TGA of Polymers 117 10.3.2 TGA of Plasticizers 118 10.3.3 TGA of Active Pharmaceutical Ingredients 119 10.4 Specifi c Heat Capacity of Polymers 120 10.5 API Solubility Enhancement of Polymers 121

Get Price
taste masking of griseofulvin and caffeine anhydrous using

Taste Masking of Griseofulvin and Caffeine Anhydrous Using

Taste masking of bitter active pharmaceutical ingredient (API) is a major challenge especially for pediatric/geriatric formulations. Effective taste masking can be achieved by various reported approaches like fluidized-bed coating, supercritical fluids, complexing agents, pro-drug approach, etc. ( 1 – 3 ).

Get Price
development of renewable resource–based cellulose acetate

Development of renewable resource–based cellulose acetate

Miguel Chávez Gutiérrez, Marco-Aurelio De Paoli, Maria Isabel Felisberti, Biocomposites based on cellulose acetate and short curauá fibers: Effect of plasticizers and chemical treatments of the fibers, Composites Part A: Applied Science and Manufacturing, 10.1016/j.compositesa.2012.03.006, 43, 8, (1338-1346), (2012).

Get Price
a systemic approach on understanding the role of moisture

A systemic approach on understanding the role of moisture

Arigo A, Jawahar N, Nikhitha S, Arun R. Effect of hygroscopicity on pharmaceutical ingredients, methods to determine and overcome: an overview. J Chem Pharm Res 2018; 10: 61-67. Claes A, George Z. The molecular basis of moisture effects on the physical and chemical stability of drugs in the solid state. Int J Pharm 1990; 67: 87-95.

Get Price
de4239244a1 - retard form for active pharmaceutical

DE4239244A1 - Retard form for active pharmaceutical

DE4239244A1 DE19924239244 DE4239244A DE4239244A1 DE 4239244 A1 DE4239244 A1 DE 4239244A1 DE 19924239244 DE19924239244 DE 19924239244 DE 4239244 A DE4239244 A DE 4239244A DE 4239244 A1 DE4239244 A1 DE 4239244A1 Authority DE Germany Prior art keywords characterized active ingredient range plasma slow release Prior art date 1992-11-21 Legal status (The legal status is an assumption and is not a ...

Get Price
basics of compounding: hot melt extrusion

Basics of Compounding: Hot Melt Extrusion

Author: DePasquale Seth, Year: 2017, Abstract: Hot Melt Extrusion, a production process that has been around for quite some time, has the ability to produce innovative compounds not previously achievable with conventional methods. However, many variables need to be considered prior to production. The use of small-scale extruders and 3D printers provides compounders a pathway for developing new ...

Get Price